Tag: Spike burst

Looking for burst signals

One of the most visible features of a functional Biological Neural Network (BNN) is its ability to generate synchronized spikes or burst signals, similar to those observed in living mammal brains.  Once they have reached a sufficient development stage, in particular in terms of connectivity, in vitro neuronal cultures tend to exhibit spontaneous bursts of …

February 4, 2020 Read more

Diversity of biological neural network cultures

The core component of  a Biological Neural Network (BNN) unit is the biological culture of neural cells. There are two main approaches to setup a BNN culture: extracting neurons at early development stage from non-human brains, for instance cortical neurons from postnatal rat brain, or differentiating stem cells such as human induced pluripotent stem cells …

October 4, 2019 Read more

Processing signals from cultured neurons

The signals read from a Biological Neural Network (BNN) unit are complex signals which require dedicated processing. Depending on the MEA spatial density and temporal resolution, gigabits of uncompressed signal data may be generated every minute. While low-scale signal analysis such as identifying the presence or absence of spike bursts may be sufficient for certain …

August 12, 2019 Read more